北海道大学 大学院総合化学院 総合化学専攻Hatching stimulation activity of steroidal glycoalkaloids toward the potato cyst nematode, Globodera rostochiensis
Shimizu, K.; Kushida, A.;Akiyama, R.; Lee, H. J.; Okamura, Y.; Masuda, Y.; Sakata, I.; Tanino, K.; Matsukida, S.; Inoue, T.; Sugimoto, Y.; Mizutani, M.
Plant Biotechnology 2020, 37, 319. DOI: 10.5511/plantbiotechnology.20.0516a
Formal Total Synthesis of Atropurpuran
Suzuki, T.; Koyama, T.; Nakanishi, K.; Kobayashi, S.; Tanino, K.
J. Org. Chem. 2020, 85, 10125. DOI: 10.1021/acs.joc.0c01462
新規化合物及びその製造方法
谷野圭持、鈴木孝洋、和田善行、村西修一、眞田慎吾
特開2020-59676, 2020-04-16
Delevopment of a 1,3a,6a-triazapentalene derivative as a compact and thiol-specific fluorecent labeling reagent.
Nakayama, A.; Otani, A.; Inokuma, T.; Tsuji, D.;Mukaiyama, H.; Nakayama, A.;Itoh, K; Otaka, K.; Tanino, K.; Namba K.
Communications Chemistry 2020, published online. DOI: 10.1038/s42004-019-0250-0
Inhibition of Lipid Droplet Formation by Ser/Thr Protein Phosphatase PPM1D Inhibitor, SL-176.
Kamada, R.; Kimura, N.; Yoshimura, F.; Tanino, K.; Sakaguchi, K.
PLOS ONE, Published online. DOI: 10.1371/journal.pone.0212682
Synthetic study of andrastins: stereoselective construction of the BCD-ring system
Yoshimura, F.; Abe, T.; Ishioka, Y.; Tanino, K.
J. Antibiot. 2019, ASAP. DOI: 10.1038/s41429-018-0136-x
Asymmetric Total Synthesis of Laurallene
Yoshimura, F.; Okada, T.; Tanino, K.
Org. Lett. 2019, 21 (2), pp 559–562. DOI: 10.1021/acs.orglett.8b03889
An intermolecular [4+3] cycloaddition reaction using 3-hydroxy-2-pyrone derivatives with an oxyallyl cation
Suzuki, T.; Yanagisawa, T.; Tanino, K.
Heterocycles 2019, 99 (2), pp 848-855. DOI: 10.3987/COM-18-S(F)79
Synthesis of Substituted Cyclopentenol Derivatives via Intramolecular Addition Reaction of Vinylcopper Species
Yamaga, H; Tanino, K.
Synlett, 2019, 30(02), 230-234. DOI: 10.1055/s-0037-1611366
Asymmetric Total Synthesis of Brasilicardins
Yoshimura, F.; Ito, R.; Torizuka, M.; Mori, G.; Tanino, K.
Angew. Chem. Int. Ed. 2018, 57, 17161-17167. DOI: 10.1002/anie.201811403
Asymmetric Total Synthesis of (−)-Maldoxin, a Common Biosynthetic Ancestor of the Chloropupukeananin Family
Suzuki, T.; Watanabe, S.; Uyanik, M.;Ishihara, K.; Kobayashi, S.;Tanino, K.
Org. Lett. 2018, 20 (13), pp 3919–3922. DOI: 10.1021/acs.orglett.8b01502
Inhibition of Ser/Thr phosphatase PPM1D induces neutrophil differentiation in HL-60 cells
Kamada, R.; Kudoh, F.; Yoshimura, F.; Tanino, K.; Sakaguchi, K.
J. Biochem. 2017, 162, 303. DOI: 10.1093/jb/mvx032
Nucleophilic Addition of Alkanenitriles to Aldehydes via In Situ Generated N-Silyl Ketene Imines
Yoshimura, F.; Saito, H.; Abe, T.; Tanino, K.
Synlett. 2017, 28, 1816. DOI: 10.1055/s-0036-1588424
Non-reductive decyanation reactions of disubstituted malononitrile derivatives promoted by NaHMDS
Domon, D.; Iwakura, M.; Tanino, K.
Tetrahedron Lett. 2017, 58, 1957. DOI: 10.1016/j.tetlet.2017.04.012
Synthetic studies on psiguadial B: Construction of bicyclo[4.3.1]decane skeleton via double cyclization reaction of alkyne dicobalt complex
Kinebuchi, M.; Uematsu, R.; Tanino, K.
Tetrahedron Lett. 2017, 58, 1382. DOI: 10.1016/j.tetlet.2017.02.058
Construction of bicyclic systems containing an oxygen bridge by isomerization of cyclic epoxy alcohols
Iwakura, M.; Tokura, H.; Tanino, K.
Tetrahedron Lett. 2017, 58, 1223. DOI: 10.1016/j.tetlet.2017.02.023
Enantioselective Total Synthesis of (+)-Iso-A82775C, a Proposed Biosynthetic Precursor of Chloropupukeananin
Suzuki, T.; Soichiro, W.; Kobayashi, S.; Tanino, K.
Org. Lett. 2017, 19 ,922. DOI: 10.1021/acs.orglett.7b00085
Facile Guanidine Formation under Mild Acidic Conditions
Takeuchi, K.; Nakayama, A.; Tanino, K.; Namba, K.
Synlett. 2016, 27, 2591. DOI: 10.1055/s-0035-1562478
Synthetic studies on enfumafungin: stereoselective synthesis of the CD ring segment
Fujitani, M.; Tanino, K.
Tetrahedron Lett. 2016, 57, 4838. DOI: 10.1016/j.tetlet.2016.09.057
Effective Cellular Morphology Analysis for Differentiation Processes by a Fluorescent 1,3a,6a-Triazapentalene Derivative Probe in Live Cells
Kamada, R.; Tano, F.; Kudoh, F.; Kimura, N.; Chuman, Y.; Osawa, A.; Namba, K.; Tanino. K.; Sakaguchi, K.
PLOS ONE 2016, 11, 8. DOI: 10.1371/journal.pone.0160625
Substituent Effect at the C4-Position of 1,3a,6a-Triazapentalene
Nakayama, A.; Nishio, S.; Otani, A.; Mera, A.; Osawa, A.; Tanino, K; Namba, K.
Chem. Pharm. Bull. 2016, 64, 7, 830. DOI: 10.1248/cpb.c16-00196
Synthesis of Aryl Amine Derivatives from Benzyl Nitriles via Electrocyclization of in Situ Generated N-Silyl Ketene Imines
Yoshimura, F.; Abe, T.; Tanino, K.
Organic Letters 2016, 18, 1630. DOI: 10.1021/acs.orglett.6b00490
Total Synthesis of palau' amine
Namba, K.; Takeuchi, K.; Kaihara, Y.; Oda, M.; Nakayama, A.;Nakayama, A.; Yoshida, M.; Tanino, K.
Nature Communications 2015, 68731. DOI: 10.1038/ncomms9731
Novel inhibitors targeting PPM1D phosphatase potently suppress cancer cell proliferation
Ogasawara, S.; Kiyota, Y.; Chuman, Y.; Kowata, A.; Yoshimura, F.; Tanino, K.; Kamada, R.; Sakaguchi, K.
Bioorg. Med. Chem. 2015, 236246. DOI: 10.1016/j.bmc.2015.08.042
Acid-Catalyzed [4+3] Cycloaddition Reaction of N-Nosyl Pyrroles
Shibata, M.; Fuchigami, R.; Namba, K.; Tanino, K.
Tetrahedron 2015, 714495. DOI: 10.1016/j.tet.2015.02.071
Synthesis of Yellow and Red Fluorescent 1,3-a,6a-Triazapentalene and Theoretical Investigation of Optical Properties
Namba, K.; Osawa, A.; Nakayama, A. ; Mera, A.; Tano, F.; Sakuda, E.; Taketsugu, T.; Sakaguchi, K.; Tanino, K.
Chem. Sci. 2015, 61083. DOI: 10.1039/C4SC02780A
Synthetic Studies on Azadirachin: Construction of the ABC Ring System via the Diels-Alder Reaction of a Vinyl Allenylsilane Derivative
Sakurai, K.; Tanino, K.
Tetrahedron Lett. 2015, 56496. DOI: 10.1016/j.tetlet.2014.12.062
Inhibition of C-terminal Truncated PPM1D Enhances the Effect of Doxorubicin on Cell Viability in Human Colorectal Carcinoma Cell Line
Kozakai, K.; Kamada, R.; Kiyota, Y.; Yoshimura, F.; Tanino, K.; Sakaguchi, K.
Bioorg. Med. Chem. Lett. 2014, 245593. DOI: 10.1016/j.bmcl.2014.10.093
N-Acyl-N-tosylhydrazine as a Synthon To Construct Tetrasubstituted Carbon Centers Possessing a Nitrogen Group
Namba, K.; Shobo, Y.; Fujimoto, K.; Shoji, I.; Yoshida, M.; Tanino, K.
Eur. J. Org. Chem. 2014, 5196. DOI: 10.1002/ejoc.201402650
Recent developments in the synthesis of zoanthamine alkaloids
Yoshimura, F.; Tanino, K.; Miyashita, M.
Tetrahedron Lett. 2014, 55, 2895. DOI: 10.1016/j.tetlet.2014.03.073
Nucleophilic Addition Reactions of Nitriles to Nitorones under Mild Silylation Conditions
Yoshimura, F.; Abe, T.; Tanino, K.
Synlett 2014, eFirst DOI: 10.1055/s-0034-1378274
Cyanoazulene-based Multistage Redox Systems Prepared from Vinylcyclopropanecarbonitrile and Cyclopentenone via Divinylcyclopropane-rearrangement Approach
Tanino, K.; Yamada, T.; Yoshimura, F.; Suzuki, T.
Chem. Lett. 2014, 43, 607. DOI: 10.1246/cl.131149
Synthesis of 1-acetyl-2-silyoxycycloheptane derivatives via highly stereoselective formal [5+2] cycloaddition reaction
Kudo, M.; Kondo, F.; Maekawa, H.; Shimizu, T.; Tanino, K.
Tetrahedron Lett. 2014, 55, 1192. DOI: 10.1016/j.tetlet.2013.12.102
Stereoselective synthesis of the right-hand segment of tubiferal A
Hiramatsu, T.; Takahashi, M.; Tanino, K.
Tetrahedron Lett. 2014, 55, 1145. DOI: 10.1016/j.tetlet.2013.12.069
Synthetic studies on taxanes: construction of the tricyclic skeleton on the basis of a [6+2] cycloaddition reaction
Hanada, R.; Mitachi, K.; Tanino, K.
Tetrahedron Lett. 2014, 55, 1097. DOI: 10.1016/j.tetlet. 2013.12.096
SYNTHESIS OF TETRASUBSTITUTED PYRROLIDINE DERIVATIVES EMPLOYING β-LACTAM AS A CHIRAL BUILDING BLOCK
Tadano, G.; Ishikura, K.; Tanino, K.
Heterocycles 2013, 87, 2267. DOI: 10.3987/COM-13-12812
Transformations of 1-(Oxianylmethy)-1,2,3-triazoles into 2-(Oxiranylmethyl)-1,2,3-triazoles and Alkanenitriles
Osawa, A.; Mera, A.; Namba, K.; Tanino, K.
Synlett 2013, 24, 207. DOI: 10.1055/s-0032-1317937
Synthesis of 2-cyano-1,4-cycloheptadiene derivatives via divinylcyclopropane rearrangement and alkylation of novel cycloheptadienyl anion species
Yamada, T.; Yoshimura, F.; Tanino, K.
Tetrahedron. Lett. 2013, 54, 522. DOI: 10.1016/j.tetlet.2012.11.070
One-Pot Synthesis of Highly Fluorescent 2,5-Disubstituted-1,3a,6a-triazapentalene
Namba, K.; Mera, A.; Osawa, A.; Sakuda, E.; Kitamura, N.; Tanino, K.
Org. Lett. 2012, 14, 1222. DOI: 10.1021/ol302668y
Total Synthesis of Zoanthamine Alkaloids
Yoshimura, F.; Miyashita, M.; Tanino, K.
ACCOUNTS OF CHEMICAL RESEARCH 2012, 45, 746. DOI: 10.1021/ar200267a
Stereocontrolled synthesis of carbocyclic compounds with a quaternary carbon atom based on SN2’ alkylation of γ,δ-epoxy-α,β-unsaturated ketones
Yoshimura, F.; Kowata, A.; Tanino, K.
Org. Biomol. Chem. 2012, 10, 5431. DOI: 10.1039/c2ob25719j
Concise [4+3] cycloaddition reaction of pyrroles leading to tropinone derivatives
Fuchigami, R.; Namba, K.; Tanino, K.
Tetrahedron Lett. 2012, 53, 5725. DOI: 10.1016/j.tetlet. 2012.07.130
A small molecule inhibitor of p53-inducible protein phosphatase PPM1D
Yagi, H.; Chuman, Y.; Kozakai, Y.; Imagawa, T.; Takahashi, Y.; Yoshimura, F.; Tanino, K.; Sakaguchi, K.
Bioorg. Med. Chem. Lett. 2012, 22, 729. DOI: 10.1016/j.bmcl.2011.10.084
Hg(OTf)2-Catalyzed Vinylogous Semi-Pinacol Rearrangement Leading to 1,4-Dihydroquinolines.
Namba, K.; Kanaki, M.; Suto, H.; Nishizawa, M.; Tanino, K.
Org. Lett. 2012, 14, 1222. DOI: 10.1021/ol2034492
Intramolecular Conjugate Addition of a,b-Unsaturated Lactones Having an Alkanenitrile Side Chain: Stereocontrolled Construction of Carbocycles with Quaternary Carbon Atoms.
Yoshimura, F.; Torizuka, M.; Mori, G.; Tanino, K.
Synlett 2011, 23, 251. DOI: 10.1055/s-0031-1290074
Direct Synthesis of Fluorescent 1,3a,6a-Triazapentalene Derivatives via Click-Cyclization-Aromatization Cascade Reaction.
Namba, K.; Osawa, A.; Ishizaka, S.; Kitamura, N.; Tanino, K.
J. Am. Chem. Soc. 2011, 133, 11466. DOI: 10.1021/ja203917r
Total Synthesis of Solanoeclepin A.
Tanino, K.; Takahashi, M.; Tomata, Y.; Tokura, H.; Uehara, T.; Narabu, T.; Miyashita, M.
Nature Chem. 2011, 3, 484. DOI: 10.1038/nchem.1044
Formal [6+4] cycloaddition of a dicobalt acetylene complex with furan derivatives.
Dota, K.; Shimizu, T.; Hasegawa, S.; Miyashita, M.; Tanino, K.
Tetrahedron Lett. 2011, 52, 910. DOI: 10.1016/j.tetlet.2010.12.063
Synthetic Studies of the Zoanthamine Alkaloids: Total Synthesis of Zoanthenol Based on an Isoaromatization Strategy.
Yoshimura, F.; Takahashi, Y.; Tanino, K.; Miyashita, M.
Chem. Asian J. 2011, 6, 922. DOI: 10.1002/asia.201000552
